Cyromazine: The Fly Larvicide That Cuts the Problem at Its Source
HESHAM MAHMOUD
HESHAM MAHMOUD
11 November 2026

What is cyromazine? An insect growth regulator specialised for fly larvae. It does not kill flying flies; it works on maggots before they become flies: it disrupts their moulting so they die without completing development. It is applied at breeding sites such as manure and waste.

How does it work?

A fly larva grows by shedding its skin several times, then becomes a pupa, then a fly.

Cyromazine upsets that process:

  • The larva cannot form a sound new skin.
  • It becomes deformed and dies before becoming a pupa or fly.
  • Adult flies are not affected.

Why treat larvae at all?

The flies you see are a small part of the problem. Most of the population is maggots at breeding sites, producing new flies every day.

  • Spraying flying flies kills what is present; tomorrow more emerge.
  • Treating larvae cuts off the source.
  • Both together is the solution.

Where is it applied?

  • Poultry and livestock houses: on manure and litter.
  • Waste collection points and organic refuse.
  • Compost and manure heaps.
  • Any moist spot with organic matter where you see maggots.

Application methods

MethodWhen
Dry scatterManure and waste that is already moist
Dissolved and sprayedDry sites or when better distribution is needed
Dissolved and pouredSmall areas and specific spots

The amount per square metre comes from the label.

When do you see results?

Not on day one. Existing adult flies live out their lives.

  • One to two weeks: fly numbers start falling, because no new generation emerges.
  • In a hurry? Use a fly bait or adulticide alongside it in the same period.

Rotate; do not rely on it alone

  • Flies can develop resistance if it is used alone year after year.
  • Alternate with a larvicide from another family.
  • Remove manure and waste promptly; this takes pressure off the product.

Safety

  • Keep away from feed and drinking water.
  • Gloves and a mask when scattering or spraying.
  • Wash your hands after use.

Products from Orkida

Cyromazine FAQs

Does cyromazine kill flying flies?

No, it is for larvae only. Adult flies need a bait or another insecticide.

Does it work on mosquito larvae?

It is specialised for flies. Mosquito larvae have their own larvicides applied to water.

How often should I repeat it?

As the label says and as manure and waste build up. New manure is not covered by an earlier treatment.

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